Can Brain Surgery Cure Epilepsy?

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Can Brain Surgery Cure Epilepsy?

Epilepsy surgery or what is commonly called brain surgery, is one of the available modalities for treating epilepsy, where the area of the brain that causes seizures is removed. This is primarily reserved for epilepsy that is poorly controlled by medication, also called drug refractory epilepsy. The first choice for the treatment of epilepsy always remains medication. In any patient with epilepsy, the underlying cause of the epilepsy drives how long the affected individual would require one or multiple medications and the duration of the disease. When the affected individual is on good doses of more than two medications, we need to always at least consider epilepsy surgery, as often the need for more than two medicines implies that the quality of life of the child or individual would be adversely impacted. By this definition many epilepsy patients would qualify for epilepsy surgery. While the thought of surgery always strikes a bit of fear, for us specialists who are very aware of what havoc uncontrolled epilepsy wrecks on the lives of patients and families not only in its unpredictability but also on the change in the quality of life and social participation, when a patient is eligible for surgery, this is often good news as there is a possibility of a cure and seizure freedom. This is true in the case of children and young people as they have a longer life ahead and thus can hopefully have a more productive life with many years ahead.

Why do we consider Epilepsy surgery in medication refractory or drug refractory epilepsy?

Epilepsy surgery or what is commonly called brain surgery is one of the available modalities for treating epilepsy, where the area of the brain that causes seizures is removed. This is primarily reserved for epilepsy that is poorly controlled by medication, also called drug-refractory epilepsy. The first choice for the treatment of epilepsy always remains medication. In any patient with epilepsy, the underlying cause of epilepsy drives how long the affected individual would require one or multiple medications and the duration of the disease. When the affected individual is on good doses of more than two medications, we need to always at least consider epilepsy surgery, as often the need for more than two medicines implies that the quality of life of the child or individual would be adversely impacted. By this definition, many epilepsy patients would qualify for epilepsy surgery. While the thought of surgery always strikes a bit of fear, for us specialists. Broadly speaking epilepsy surgery could be classified into respective or curative surgery. Curative surgery aims at a cure and palliative surgery aims at improving quality of life, but is still considered, especially when there are severe difficulties, such as seizures as frequent as 50 or more a day! Some of the palliative measures also include techniques such as placing implants like a Vagal nerve stimulator (VNS) which would change the neurochemical environment within the brain, thus reducing the likelihood of seizures. Discussing the various techniques and types of epilepsy surgery would not be as important as trying to understand the whys and wherefores of epilepsy surgery. While talking about curative and resective surgery, the onus is on the epilepsy surgical team to prove that the seizures originate from one region of the brain, and that removing that part of the brain, would not cause an unacceptable deficit, such as weakness in a body part etc. Since most children who are appropriately vetted and chosen as epilepsy surgery candidates do well, with a significant proportion even becoming seizure free and the rest of them showing significant improvement, we in the field of child neurology are always gratified and pleased to see this as a possibility. This is a very technology and specialist intensive field as it requires a high level of coordination between various specialists, mainly the neuro physician, the neuro surgeon, the MRI specialist as well close working with specialists reading the electrical activity of the brain and rehabilitation experts post operatively. All of this work up is mandatory before we proceed to surgery and this takes time and effort. This process is called epilepsy surgery evaluation and doing this well is the key for successful outcomes. We need more of such comprehensive centers for epilepsy surgical management as this would improve the lives of many of our children affected with epilepsy.  

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